Author

V. Posse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

A. P. Bertolin· 2 shared B. Canal· 2 shared F. Weissmann· 2 shared J. F. Diffley· 2 shared J. Milligan· 2 shared J. Zeng· 2 shared L. S. Drury· 2 shared M. Howell· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. P. Bertolin

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2 papers

Recent·Most cited

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp12/7/8 RNA-dependent RNA Polymerase

R. Beale, A. P. Bertolin, B. Canal, J. F. Diffley, L. S. Drury, M. Howell, J. Milligan, V. Posse, R. Ulferts, F. Weissmann, M. Wu, J. Zeng

This study screens a chemical library to identify SARS-CoV-2 RdRp inhibitors, finding three novel compounds and confirming suramin-like compounds as inhibitors.

bioRxiv · Apr 7, 2021Biochemistry

Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase

R. Beale, A. P. Bertolin, A. Borg, B. Canal, J. F. Diffley, L. S. Drury, R. Harvey, M. Howell, S. Hussain, S. Kjaer, J. McCauley, L. McCoy, J. Milligan, V. Posse, C. Roustan, , J. Zeng

This study identifies small molecule inhibitors of SARS-CoV-2 nsp13 helicase by screening a chemical library and validates their antiviral efficacy in cell culture.

bioRxiv · Apr 7, 2021Biochemistry