BiochemistrybioRxiv
Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations
V. Seplyarskiy, E. E. Akkuratov, N. V. Akkuratova…·S. R. Sunyaev
The paper identifies error-prone bypass of DNA lesions on the lagging strand as a major source of human germline and cancer mutations, supported by mutational asymmetry analysis and experimental validation.
DOI 10.1038/s41588-018-0285-7