Author

I. Adameyko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:development & morphogenesis· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P. Kogner· 2 shared T. Martinsson· 2 shared A. Akovantseva· 1 shared A. Bjoerklund· 1 shared A. Chan· 1 shared A. D. Kurenkova· 1 shared A. Eriksson· 1 shared A. Johansson· 1 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCancer Biology

P. Kogner

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Author profile →

6 papers

Recent·Most cited

Theory of branching morphogenesis by local interactions and global guidance

M. C. Ucar, D. Kamenev, K. Sunadome, D. Fachet, F. Lallemend, I. Adameyko, S. Hadjab, E. Hannezo

This study develops a theoretical framework to analyze how global and local cues influence branching morphogenesis, using zebrafish innervation as a model system.

bioRxiv · Aug 30, 2021Biophysics

An immature subset of neuroblastoma cells synthesizes retinoic acid and depends on this metabolite

T. van Groningen, C. U. Niklasson, A. Chan, N. Akogul, E. M. Westerhout, K. von Stedingk, M. Hamdi, L. J. Valentijn, S. Mohlin, P. Stroeken, N. E. Hasselt, F. Haneveld, A. Lakeman, D. A. Zwijnenburg, P. van Sluis, , J. van Nes

The paper identifies an immature neuroblastoma subset that synthesizes retinoic acid and is resistant to it, potentially contributing to therapy-resistant relapses.

bioRxiv · May 18, 2021 · PreprintCancer Biology

Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumors.

O. C. Bedoya-Reina, W. Li, M. Arceo, M. Plescher, P. Bullova, H. Pui, M. Kaucka, P. Kharchenko, T. Martinsson, J. Holmberg, I. Adameyko, Q. Deng, C. Larsson, C. Juhlin, P. Kogner, S. Schlisio

The paper identifies distinct cellular identities in low and high-risk neuroblastoma tumors using single-nuclei transcriptomes, linking them to clinical outcomes and age at diagnosis.

bioRxiv · Mar 26, 2021Cancer Biology

Secondary ossification center induces and protects growth plate structure

M. Xie, P. Goldin, A. N. Herdina, J. Estefa, E. Medvedeva, L. Li, P. Newton, S. Kotova, B. Shavkuta, A. Saxena, L. Shumate, B. Metscher, K. Groschmidt, S. Nishimori, A. Akovantseva, , A. S. Chagin

This study identifies the secondary ossification center's role in protecting growth plate hypertrophic chondrocytes from mechanical stress during terrestrial adaptation.

bioRxiv · Sep 1, 2020Evolutionary Biology

Malignant Schwann cell precursors mediate intratumoral plasticity in human neuroblastoma

T. K. Olsen, J. Otte, S. Mei, P. Kameneva, A. Bjoerklund, E. Kryukov, Z. Hou, A. Johansson, E. Sundstroem, T. Martinsson, S. Fransson, J. I. Johnsen, P. Kogner, I. Adameyko, P. V. Kharchenko, N. Baryawno

The paper identifies a subpopulation of malignant Schwann cell precursor-like cells in neuroblastoma that connects adrenergic and mesenchymal tumor cells, suggesting intratumoral plasticity mechanisms.

bioRxiv · May 4, 2020 · PreprintCancer Biology

Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations

V. Seplyarskiy, E. E. Akkuratov, N. V. Akkuratova, M. A. Andrianova, S. I. Nikolaev, G. A. Bazykin, I. Adameyko, S. R. Sunyaev

The paper identifies error-prone bypass of DNA lesions on the lagging strand as a major source of human germline and cancer mutations, supported by mutational asymmetry analysis and experimental validation.

bioRxiv · May 26, 2018Biochemistry