Author

V. Siewers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5

Signature Assays, Organisms & Methods

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Organism:yeast· 5 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

F. David· 3 shared J. Nielsen· 2 shared M. Otto· 2 shared A. Bergman· 1 shared C. Picazo· 1 shared K. Campbell· 1 shared L. Wenning· 1 shared M. Gossing· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBioengineering

F. David

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Engineering Yeast to Improve Heterologous Abscisic Acid Production

M. Otto, M. Gossing, F. David, V. Siewers

This study improves heterologous abscisic acid production in yeast by identifying PAH1 gene fine-tuning as a promising engineering strategy.

bioRxiv · Jun 7, 2023 · PreprintBioengineering

Sense and Screen-ability: Development of tuneable, biosensor-based screening platforms for abscisic acid

M. Otto, Y. Dabirian, F. David, V. Siewers

The paper develops tunable biosensor-based screening platforms for optimizing ABA-producing enzymes in yeast.

bioRxiv · May 16, 2023 · PreprintBioengineering

The yeast eIF2 kinase Gcn2 facilitates H2O2-mediated feedback inhibition of both protein synthesis and ER oxidative folding during recombinant protein production

V. Gast, K. Campbell, C. Picazo, M. K. M. Engqvist, V. Siewers, M. Molin

This study shows that Gcn2 kinase mediates H2O2 feedback inhibition of protein synthesis and ER oxidative folding in yeast during recombinant protein production, and its removal enhances -amylase production.

bioRxiv · Feb 3, 2021Bioengineering

Investigation of putative regulatory acetylation sites in Fas2p of Saccharomyces cerevisiae

A. Bergman, L. Wenning, V. Siewers, J. Nielsen

This study investigates the regulatory impact of acetylation sites on Fas2p in yeast by mutating lysine residues to glutamine or arginine and analyzing effects on fatty acid biosynthesis.

bioRxiv · Sep 29, 2018 · PreprintBioengineering

Engineering Lipid Droplet Assembly Mechanisms for Improved Triacylglycerols Accumulation in S. cerevisiae

P. G. Teixeira, F. David, V. Siewers, J. Nielsen

This study improves triacylglycerol accumulation in S. cerevisiae by engineering lipid droplet assembly mechanisms, achieving up to 138% higher TAG levels without affecting growth or morphology.

bioRxiv · Feb 6, 2018Bioengineering