A. Bergman

Atypical landscape of transposable elements in the large genome of Aedes aegypti

This study compares transposable element organization in the large Aedes aegypti genome to smaller Diptera genomes, finding higher TE transposition and lower elimination rates in Ae. aegypti.

Haematopoietic stem cell numbers are not solely determined by niche availability

This study challenges the idea that HSC numbers are solely determined by niche availability, showing systemic and local constraints on HSC numbers regardless of niche changes.

Chaotic signatures in host-microbe interactions

This study investigates whether time-to-death datasets can reveal chaotic signatures in host-microbe interactions using simulated and experimental data from C. elegans and Drosophila infected with Pseudomonas species.

Bet-hedging antimicrobial strategies in macrophage phagosome acidification drive the dynamics of Cryptococcus neoformans intracellular escape mechanisms

This study identifies that stochastic phagosomal acidification and oxidative stress drive stochastic Dragotcytosis in Cryptococcus neoformans, enabling fungal escape from macrophages.

Macrophages utilize a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification

The paper shows macrophages use a bet-hedging strategy by stochastically acidifying phagolysosomes to reduce variation in antimicrobial effectiveness.

Evolutionary contingency’s impact on laboratory evolution of Escherichia coli under fluctuating environments

This study evolves Escherichia coli under fluctuating temperature regimes to examine evolutionary contingency and adaptation strategies, finding distinct genetic and phenotypic responses depending on initial genetic background.

Investigation of putative regulatory acetylation sites in Fas2p of Saccharomyces cerevisiae

This study investigates the regulatory impact of acetylation sites on Fas2p in yeast by mutating lysine residues to glutamine or arginine and analyzing effects on fatty acid biosynthesis.

ECM cross-linking regulates invadopodia dynamics

This study shows that ECM cross-linking levels non-linearly affect invadopodia dynamics and ECM degradation in cancer cells, with intermediate cross-linking promoting maximal degradation.