Label-free sensing of cells with fluorescence lifetime imaging: the quest for metabolic heterogeneity
E. A. Shirshin, M. V. Shirmanova, A. V. Gayer, M. M. Lukina, E. E. Nikonova, B. P. Yakimov, G. S. Budylin, V. V. Dudenkova, N. I. Ignatova, D. V. Komarov, V. V. Yakovlev, W. Becker, E. V. Zagaynova, V. V. Shcheslavskiy, M. O. Scully
This study demonstrates a novel FLIM data analysis approach to better detect metabolic heterogeneity in cancer cells, validated through chemotherapy-treated cell imaging.
bioRxiv · Jan 12, 2022Cancer Biology