Author

E. E. Nikonova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

E. A. Shirshin· 2 shared M. V. Shirmanova· 2 shared N. I. Ignatova· 2 shared A. D. Komarova· 1 shared A. M. Mozherov· 1 shared A. V. Gayer· 1 shared B. P. Yakimov· 1 shared D. V. Komarov· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

E. A. Shirshin

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2 papers

Recent·Most cited

Metabolic heterogeneity of colorectal cancer as a prognostic factor: insights gained from fluorescence lifetime imaging

A. D. Komarova, S. D. Sinyushkina, I. D. Shchechkin, I. N. Druzhkova, S. A. Smirnova, V. M. Terekhov, A. M. Mozherov, N. I. Ignatova, E. E. Nikonova, E. A. Shirshin, L. E. Shimolina, S. V. Gamayunov, V. I. Shcheslavskiy, M. V. Shirmanova

This study uses fluorescence lifetime imaging to quantify metabolic heterogeneity in colorectal cancer, finding higher heterogeneity in patient tumors compared to cell lines and xenografts, with potential prognostic value.

bioRxiv · Jan 2, 2024Cancer Biology

Label-free sensing of cells with fluorescence lifetime imaging: the quest for metabolic heterogeneity

E. A. Shirshin, M. V. Shirmanova, A. V. Gayer, M. M. Lukina, E. E. Nikonova, B. P. Yakimov, G. S. Budylin, V. V. Dudenkova, N. I. Ignatova, D. V. Komarov, V. V. Yakovlev, W. Becker, E. V. Zagaynova, V. V. Shcheslavskiy, M. O. Scully

This study demonstrates a novel FLIM data analysis approach to better detect metabolic heterogeneity in cancer cells, validated through chemotherapy-treated cell imaging.

bioRxiv · Jan 12, 2022Cancer Biology