V. Yechoor

A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system

This paper develops a coupled microphysiological system to study how liver dysfunction affects pancreatic islet function, finding altered secretomes and glucose responses under metabolic syndrome conditions.

The clock-modulatory activity of Nobiletin suppresses adipogenesis via Wnt signaling

This study shows Nobiletin suppresses adipogenesis by enhancing the circadian clock and activating Wnt signaling, leading to reduced fat mass and body weight in mice.

Circadian clock control of MRTF-SRF signaling suppresses beige adipocyte thermogenic recruitment

This study identifies a circadian clock control of MRTF-SRF signaling that suppresses beige adipocyte thermogenic recruitment and maintains metabolic homeostasis.