Author

Valentin Thron

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anne R. GoodingiD· 1 shared Annette H. ErbseiD· 1 shared Jiarui SongiD· 1 shared Karen J. GoodrichiD· 1 shared Liqi YaoiD· 1 shared Thomas R. CechiD· 1 shared Vignesh KasinathiD· 1 shared Wayne O. HemphilliD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Anne R. GoodingORCID

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1 paper

Recent·Most cited

RNA-induced PRC2 inhibition depends on the sequence of bound RNA

Jiarui Song, Liqi Yao, Anne R. Gooding, Valentin Thron, Wayne O. Hemphill, Karen J. Goodrich, Annette H. Erbse, Vignesh Kasinath, Thomas R. Cech

This study shows that RNA sequence determines whether it inhibits PRC2 methyltransferase activity by dimerizing the complex or retains its activity by binding monomers.

Nature Communications · Apr 23, 2026Peer-reviewedBiochemistry