Heterogeneity of hypothalamic Pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
Brian Lam, Irène Cimino, Joseph Polex-Wolf, Sara Kohnke, Debra Rimmington, Valentine Iyemere, Nicholas Heeley, Chiara Cossetti, Reiner Schulte, Luís R. Saraiva, Darren W. Logan, Clémence Blouet, Stephen O’Rahilly, Anthony P. Coll, Giles S.H. Yeo
The paper uses single-cell RNA sequencing to reveal heterogeneity in murine hypothalamic POMC neurons, identifying distinct subpopulations with different gene expression profiles and receptor expression.
Molecular Metabolism · Mar 1, 2017Peer-reviewedNeuroscience