Darren W. Logan

The paper investigates KPTN-related disorder using mouse and human stem cell models, identifying mTOR pathway dysregulation as a key mechanism underlying cognitive and overgrowth phenotypes.

This paper creates a 3D spatial transcriptomics atlas of the mouse olfactory mucosa, revealing spatial gene distribution patterns and supporting the chromatographic theory of olfaction.

The paper identifies non-neuronal cell types in the olfactory system expressing SARS-CoV-2 entry genes, suggesting indirect mechanisms for COVID-19-associated anosmia.

The paper examines gene expression changes across multiple organs during short-term fasting in mice, identifying a brain-liver-fats network with significant immune system regulation.

This study creates a transcriptomic atlas of olfactory mucosae across species to show evolutionary patterns in odor detection capabilities.

The paper uses single-cell RNA sequencing to reveal heterogeneity in murine hypothalamic POMC neurons, identifying distinct subpopulations with different gene expression profiles and receptor expression.