Developmental BiologyNature CommunicationsPeer-reviewed
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Claire S. Simon, Afshan McCarthy, Laura M. Woods…·Kathy K. Niakan
The paper shows that inhibiting ERK signaling expands epiblast cells capable of becoming naive pluripotent stem cells in humans, while FGF stimulation expands hypoblast markers.
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