Long-term small effective population size, inbreeding, and a recessive lethal haplotype drive premature death in the endangered Devils Hole pupfish (Cyprinodon diabolis)
David Tian, Nicolas M. Alexandre, Naomi Siu, Vanessa Muhl, Sean C. Lema, Bruce J. Turner, Olin G. Feuerbacher, Kevin P. Wilson, Michael Schwemm, Priya Moorjani, Jennifer M. Gumm, Christopher H. Martin
The paper investigates how long-term small population size and inbreeding contribute to premature death in Devils Hole pupfish using genomic and phenotypic data.
bioRxiv · Jun 10, 2026 · PreprintEvolutionary Biology