Author

Vanessa Simões

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Blanche K. CizubuiD· 2 shared Gustavo M. SilvaiD· 2 shared Chia‐Yu CheniD· 1 shared Clara M. Santos· 1 shared Dinachi A Okonkwo· 1 shared E. J. WashingtoniD· 1 shared Géssica C. BarrosiD· 1 shared Lana Harley· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Blanche K. CizubuORCID

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2 papers

Recent·Most cited

Redox control of the deubiquitinating enzyme Ubp2 regulates translation during stress

Clara M. Santos, Blanche K. Cizubu, Dinachi A Okonkwo, Chia‐Yu Chen, Natori Maske, Nathan A. Snyder, Vanessa Simões, E. J. Washington, Gustavo M. Silva

This study shows that Ubp2, a DUB, is redox-regulated during oxidative stress in yeast, controlling K63-ub chains on ribosomes and restoring translation post-stress.

Journal of Biological Chemistry · Oct 9, 2024Peer-reviewedBiochemistry

The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress

Sezen Meydan, Géssica C. Barros, Vanessa Simões, Lana Harley, Blanche K. Cizubu, Nicholas R. Guydosh, Gustavo M. Silva

The paper shows Rad6 mediates ribosome pausing during oxidative stress, affecting translation and stress response pathways.

Cell Reports · Nov 1, 2023Peer-reviewedMolecular Biology