E. Washington

This study identifies HXK1 and HXK2 as genetic suppressors of Tps1 loss-of-function in C. deneoformans, revealing their role in regulating glycolytic flux to restore thermotolerance.

This paper identifies 4456dh, a small molecule inhibitor of trehalose-6-phosphate synthase, which disrupts fungal thermal tolerance and virulence.

This study shows that Ubp2, a DUB, is redox-regulated during oxidative stress in yeast, controlling K63-ub chains on ribosomes and restoring translation post-stress.

The paper identifies a nonsynonymous ERAP1 variant associated with increased susceptibility to influenza virus using scHi-HOST, a single-cell method for genetic susceptibility testing.