Author

Vatsal Mehra

Marquette University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Murray G. BlackmoreiD· 4 shared Zimei WangiD· 4 shared Ishwariya VenkateshiD· 3 shared Advaita Chakraborty· 2 shared Erik Eastwood· 2 shared Matthew T. Simpson· 2 shared Adam Romanski· 1 shared Ben L. Callif· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersNeuroscience

Murray G. BlackmoreORCID

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4 papers

Recent·Most cited

Brain-wide quantification of the supraspinal connectome reveals anatomical correlates to functional recovery after spinal injury

Zimei Wang, Adam Romanski, Vatsal Mehra, Yunfang Wang, Matthew Brannigan, Benjamin C. Campbell, Gregory A. Petsko, Pantelis Tsoulfas, Murray G. Blackmore

The paper quantifies the supraspinal connectome in mice to identify anatomical correlates of functional recovery after spinal injury.

eLife · Jul 15, 2022Peer-reviewedNeuroscience

Co-occupancy analysis reveals novel transcriptional synergies for axon growth

Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Matthew T. Simpson, Erik Eastwood, Advaita Chakraborty, Zac Beine, Derek Gross, Michael Cabahug, Greta Olson, Murray G. Blackmore

The paper identifies novel transcription factor synergies that enhance axon growth by analyzing co-occupancy patterns and validating them through experimental screens and animal models.

bioRxiv · Jun 12, 2020 · PreprintNeuroscience

KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons

Zimei Wang, Vatsal Mehra, Matthew T. Simpson, Brian Maunze, Advaita Chakraborty, Lyndsey Holan, Erik Eastwood, Murray G. Blackmore, Ishwariya Venkatesh

This study shows KLF6 promotes axon growth in CNS neurons by co-occupying regulatory DNA with STAT3, leading to synergistic gene expression changes.

Scientific Reports · Aug 16, 2018Peer-reviewedNeuroscience

Developmental chromatin restriction of pro-growth gene networks acts as an epigenetic barrier to axon regeneration in cortical neurons

Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Ben L. Callif, Murray G. Blackmore

The paper develops a bioinformatic pipeline to analyze chromatin accessibility and gene networks in cortical neurons, finding that developmental chromatin restriction limits axon regeneration and identifies potential pioneer factors to overcome this barrier.

Developmental Neurobiology · May 22, 2018Peer-reviewedNeuroscience