Author

Zac Beine

Marquette University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Murray G. BlackmoreiD· 3 shared Zimei WangiD· 3 shared Ishwariya VenkateshiD· 2 shared Pantelis TsoulfasiD· 2 shared Advaita Chakraborty· 1 shared Alicia Alvarez Ribelles· 1 shared Derek Gross· 1 shared Elizabeth Batsel· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Murray G. BlackmoreORCID

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3 papers

Recent·Most cited

Injury distance limits the transcriptional response to spinal injury

Zimei Wang, Manojkumar Kumaran, Elizabeth Batsel, Sofia Testor-Cabrera, Zac Beine, Alicia Alvarez Ribelles, Pantelis Tsoulfas, Ishwariya Venkatesh, Murray G. Blackmore

This study profiles the transcriptional response of supraspinal cell types to spinal injury in mice, finding that CST neurons respond more strongly to injuries closer to the brain than to distant spinal injuries.

bioRxiv · May 27, 2024 · PreprintNeuroscience

Single nuclei analyses reveal transcriptional profiles and marker genes for diverse supraspinal populations

Zac Beine, Zimei Wang, Pantelis Tsoulfas, Murray G. Blackmore

The paper uses single nuclei RNA sequencing to identify transcriptional profiles and marker genes for supraspinal neurons projecting to the lumbar spinal cord in mice.

Journal of Neuroscience · Oct 6, 2022Peer-reviewedNeuroscience

Co-occupancy analysis reveals novel transcriptional synergies for axon growth

Ishwariya Venkatesh, Vatsal Mehra, Zimei Wang, Matthew T. Simpson, Erik Eastwood, Advaita Chakraborty, Zac Beine, Derek Gross, Michael Cabahug, Greta Olson, Murray G. Blackmore

The paper identifies novel transcription factor synergies that enhance axon growth by analyzing co-occupancy patterns and validating them through experimental screens and animal models.

bioRxiv · Jun 12, 2020 · PreprintNeuroscience