Veikko Salomaa

Genomic prediction of coronary heart disease

This study develops a genomic risk score for coronary heart disease and shows it improves risk prediction beyond clinical scores, particularly in older adults.

Whole genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

The paper compares genome sequences from Finnish and British populations to identify genetic variants enriched in a population bottleneck, finding significant enrichment of rare variants in Finns.

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

This study finds that ultra-rare disruptive variants in highly constrained genes are associated with reduced educational attainment in the general population.

Genome-wide association study identifies 17 new loci influencing concentrations of circulating cytokines and growth factors

This study identifies 17 new genetic loci associated with circulating cytokine and growth factor concentrations in Finns, linking them to immune-related diseases and potential drug targets.

Metabolic profiling of alcohol consumption in 9778 young adults

This study examines the metabolic effects of alcohol consumption in young adults, finding associations with multiple cardiometabolic risk markers and a complex metabolic signature.

metaCCA: Summary statistics-based multivariate meta-analysis of genome-wide association studies using canonical correlation analysis

metaCCA performs multivariate meta-analysis of genome-wide association studies using canonical correlation analysis, showing agreement with pooled individual-level data.

Systems medicine links microbial inflammatory response with glycoprotein-associated mortality risk

This study links elevated glycoprotein acetyls (GlycA) to chronic inflammation and microbial infection risk using integrative omics and health records.