Vicki Thallas‐Bonke

This study profiles bioenergetic changes in fresh human kidney tissue from diabetic patients with preserved function, revealing compensatory metabolic adaptation and intrinsic mitochondrial dysfunction.

This study shows that blood glucose levels directly affect mitochondrial function and metabolism in early diabetic kidney disease, with changes in proteome, metabolome, and lipidome.

This study shows that increasing OST48 expression in diabetic mice improves insulin secretion but does not prevent diabetic kidney disease despite enhancing AGE clearance.