DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance
Flora D’Anna, Laurien Van Dyck, Jieyi Xiong, Hui Zhao, Rebecca V. Berrens, Junbin Qian, Paweł Bieniasz-Krzywiec, Vikas Chandra, Luc Schoonjans, Jason B. Matthews, Julie De Smedt, Liesbeth Minnoye, Ricardo Amorim, Sepideh Khorasanizadeh, Qian Yu, , Diether Lambrechts
The paper shows DNA methylation prevents HIF binding, affecting hypoxia responses and tumour immunotolerance.
Genome biology · Jul 27, 2020Peer-reviewedGenomics