Rebecca V. Berrens

The paper introduces CELLO-seq, a long-read RNA sequencing method for single cells, to study TE expression in mouse and human cells, finding locus-specific expression and regulatory heterogeneity.

The paper shows DNA methylation prevents HIF binding, affecting hypoxia responses and tumour immunotolerance.

This study compares WGBS library preparation methods and identifies biases in sequencing data, finding that bisulfite conversion and PCR amplification are major sources of bias.