Author

Qian Yu

KU Leuven

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genomics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 4 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2

Frequent Co-Authors

Bernard ThienpontiD· 3 shared Paulien Van MinseliD· 2 shared Bingrui Zhu· 1 shared Biyun ZhengiD· 1 shared Canyu MaiD· 1 shared Chang Ming HuangiD· 1 shared Changming Liu· 1 shared Chris Van den HauteiD· 1 shared

Activity by Year

2020-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersNeuroscience

Bernard ThienpontORCID

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Author profile →

5 papers

Recent·Most cited

Protein aggregation inhibitors induce divergent transcriptional responses in a cellular model of a-synuclein seeded aggregation

Paulien Van Minsel, Chris Van den Haute, Eline Vonck, Shirine Hentati, Michele Curcio, Xinran Song, Qian Yu, Matthias Versele, Kenneth W. Young, Patrick Chaltin, Bernard Thienpont, Veronique Daniëls, Veerle Baekelandt, Wouter Peelaerts

The paper evaluates three Syn aggregation inhibitors in a cellular model of a-synuclein aggregation using single-cell RNA sequencing to identify transcriptional changes and potential druggable pathways.

npj Parkinson s Disease · Aug 26, 2026Peer-reviewedNeuroscience

Tff2 marks gastric corpus progenitors that give rise to pyloric metaplasia/SPEM following injury

Ruhong Tu, Hua-Long Zheng, Biyun Zheng, Qing Zhong, Jin Qian, Qian Yu, Feijing Wu, Toshiro Shiokawa, Yosuke Ochiai, Hiroki Kobayashi, Quin T. Waterbury, Leah B. Zamechek, Youxin Gao, Satoru Takahashi, Seiya Mizuno, , Timothy Cragin Wang

This study identifies Tff2+ progenitors in the gastric corpus as the primary source of SPEM and gastric cancer following injury, showing they can bypass metaplasia and progress directly to dysplasia.

Gut · Apr 14, 2026Peer-reviewedCell Biology

A spatiotemporal immune atlas of subarachnoid hemorrhage from single-cell and spatial transcriptomics

Changming Liu, Bingrui Zhu, Yuchun Liu, Qian Yu, Yi Chen, Jinchen Zhou, Xiaocan Wang, Canyu Ma, Yibo Liu, Guangmin Qiu, Haifeng Chu, Kaikai Wang, Jianmin Zhang, Xiaoyu Wang

This paper constructs a spatiotemporal immune atlas of subarachnoid hemorrhage using single-cell and spatial transcriptomics to identify immune cell subsets and their dynamics.

bioRxiv · Feb 9, 2026 · PreprintImmunology

GiRAFR improves gRNA detection and annotation in single cell CRISPR screens

Qian Yu, Paulien Van Minsel, Eva Galle, Bernard Thienpont

GiRAFR improves gRNA detection and annotation in single cell CRISPR screens by identifying mutant gRNAs that are dysfunctional and often overlooked by existing tools.

Communications Biology · Sep 23, 2023Peer-reviewedBioinformatics

DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance

Flora D’Anna, Laurien Van Dyck, Jieyi Xiong, Hui Zhao, Rebecca V. Berrens, Junbin Qian, Paweł Bieniasz-Krzywiec, Vikas Chandra, Luc Schoonjans, Jason B. Matthews, Julie De Smedt, Liesbeth Minnoye, Ricardo Amorim, Sepideh Khorasanizadeh, Qian Yu, , Diether Lambrechts

The paper shows DNA methylation prevents HIF binding, affecting hypoxia responses and tumour immunotolerance.

Genome biology · Jul 27, 2020Peer-reviewedGenomics