IL-27 Stablizes Myc-Mediated Transcription In Memory-Fated, Vaccine-Elicited CD8+ T Cells
Scott B. Thompson, Michael G. Harbell, John Manalastas, Daria Leonidovna Ivanova, Kent A. Riemondy, Erika L. Lasda, Vincent Chen, Jay R. Hesselberth, Anthony T. Phan, David A. Christian, Christopher A. Hunter, Tonya M. Brunetti, Laurent Gapin, Jared S. Klarquist, Ross M. Kedl
Subunit vaccines induce CD8+ T cells with memory fate characteristics that maintain proliferative capacity via IL-27 receptor signaling during expansion.
bioRxiv · Jul 31, 2024 · PreprintImmunology