Haploinsufficiency of the essential gene RpS12 causes defects in erythropoiesis and hematopoietic stem cell maintenance
Virginia Folgado-Marco, Kristina T. Ames, Jacky Chuen, Kira Gritsman, Nicholas E. Baker
This study shows that partial deletion of RpS12 in mice causes defects in erythropoiesis and hematopoietic stem cell maintenance, leading to embryonic lethality and pancytopenia.
eLife · Jun 5, 2023Peer-reviewedDevelopmental Biology