Nicholas E. Baker

This paper shows Xrp1 contributes to genome integrity through p53-dependent DNA damage response and p53-independent cell competition in Drosophila.

The paper shows that the Drosophila Id protein Emc regulates Notch signaling through non-apoptotic caspase activity, affecting eye development and cell fate decisions.

This study shows that partial deletion of RpS12 in mice causes defects in erythropoiesis and hematopoietic stem cell maintenance, leading to embryonic lethality and pancytopenia.

This study identifies Xrp1 as a master regulator that triggers cell competition and translation deficits in response to ribosomal stress.

The paper shows that cell competition eliminates segmentally aneuploid cells in Drosophila imaginal discs through the RpS12-Xrp1 pathway, dependent on differences in ribosomal protein gene dose.