Replication-dead gammaherpesvirus vaccine protects against acute replication, reactivation from latency, and lethal challenge in mice
W. A. Bland, S. M. Owens, K. McEvoy, C. H. Hogan, L. Boccuzzi, V. Kirillov, C. Khairallah, B. S. Sheridan, J. C. Forrest, L. T. Krug
This paper develops a replication-dead gammaherpesvirus vaccine that protects mice from acute replication, reactivation, and lethal disease caused by wild-type virus.
bioRxiv · Sep 26, 2023Microbiology