Author

V. Kirillov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

L. T. Krug· 3 shared C. H. Hogan· 2 shared C. Khairallah· 2 shared J. C. Forrest· 2 shared N. C. Reich· 2 shared Q. Dong· 2 shared S. M. Owens· 2 shared X. Li· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

L. T. Krug

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer

S. D'Amico, V. Kirillov, O. Petrenko, N. C. Reich

The paper identifies STAT3 as a genetic modifier of TGF-beta-induced EMT in KRAS mutant pancreatic cancer, showing its role in tumor maintenance and epithelial homeostasis.

eLife · Apr 4, 2024Peer-reviewedCancer Biology

Replication-dead gammaherpesvirus vaccine protects against acute replication, reactivation from latency, and lethal challenge in mice

W. A. Bland, S. M. Owens, K. McEvoy, C. H. Hogan, L. Boccuzzi, V. Kirillov, C. Khairallah, B. S. Sheridan, J. C. Forrest, L. T. Krug

This paper develops a replication-dead gammaherpesvirus vaccine that protects mice from acute replication, reactivation, and lethal disease caused by wild-type virus.

bioRxiv · Sep 26, 2023Microbiology

B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model

C. H. Hogan, S. M. Owens, G. V. Reynoso, V. Kirillov, T. J. Meyer, M. A. Zelazowska, B. Liu, X. Li, A. Chikhalya, Q. Dong, C. Khairallah, N. C. Reich, B. Sheridan, K. M. McBride, P. Hearing, , L. T. Krug

This study shows that B cell-intrinsic STAT3 supports gammaherpesvirus latency and suppresses interferon responses in mice, using a competitive infection model.

bioRxiv · Mar 22, 2023 · PreprintMicrobiology

IKKalpha-Mediated Non-canonical NF-kappaB Signaling is Required to Support Murine Gammaherpesvirus 68 Latency In Vivo

B. Cieniewicz, V. Kirillov, I. Daher, X. Li, D. G. Oldenburg, Q. Dong, J. A. Bettke, K. B. Marcu, L. T. Krug

This study shows that non-canonical NF-kappaB signaling via IKKalpha is essential for MHV68 latency in mice, but not for viral replication or reactivation in all cell types.

bioRxiv · Jan 5, 2022Microbiology

A role of hypoxia inducible factor 1 alpha in Mouse Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency

D. M. Lopez-Rodriguez, V. Kirillov, L. Krug, E. A. Mesri, S. Andreansky

This study investigates the role of hypoxia inducible factor 1 alpha (HIF1) in MHV68 lytic replication and reactivation, showing that HIF1 promotes virus production and reactivation from latency.

bioRxiv · Oct 3, 2019Cancer Biology