W. Apro

Anabolic sensitivity in healthy, lean, older men is associated with higher expression of amino acid sensors and mTORC1 activators

This study shows that lean, healthy older men maintain anabolic sensitivity to amino acids and exercise, with increased mTORC1 signaling and muscle protein synthesis, suggesting aging alone does not cause anabolic resistance.

Benefits of higher resistance-training volume depends on ribosome biogenesis

This study shows that moderate resistance-training volume leads to greater muscle hypertrophy and strength compared to low volume, with benefits linked to increased ribosomal biogenesis.