W. C. Ladiges

A machine learning approach for quantifying age-related histological changes in the mouse kidney.

This paper develops a machine learning model to quantify age-related histological changes in mouse kidneys, validated against pathologist scores and applied to provide reproducible age scores.

Intermittent treatment with elamipretide preserves exercise tolerance in aged female mice

This study shows that intermittent elamipretide injections in aged mice preserve exercise tolerance and skeletal muscle function but not heart or kidney function, unlike continuous treatment.

Adverse neurological effects of short-term sleep deprivation in aging mice are prevented bySS31 peptide

This study shows that SS31 peptide prevents learning impairment and restores mitochondrial function in aged mice after short-term sleep deprivation.