Type-2 CD8+ T lymphocytes responsive to PGD2 and LTE4 in severe eosinophilic asthma
B. Hilvering, T. S. Hinks, L. Stoger…·L. Xue
The paper identifies type-2 CD8+ T cells (Tc2) enriched in severe eosinophilic asthma and shows PGD2 and LTE4 drive their recruitment and activation, contributing to eosinophilia.