Author

W. D. Lees

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. M. Collins· 2 shared A. Peres· 1 shared C. A. Silver· 1 shared C. T. Watson· 1 shared C. Watson· 1 shared G. Yaari· 1 shared J. T. Kos· 1 shared K. M. Shields· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

A. M. Collins

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2 papers

Recent·Most cited

IGHV allele similarity clustering improves genotype inference from adaptive immune receptor repertoire sequencing data

A. Peres, W. D. Lees, O. L. Rodriguez, N. Y. Lee, P. Polak, R. Hope, M. Kedmi, A. M. Collins, M. Ohlin, S. H. Kleinstein, C. Watson, G. Yaari

The paper introduces a new V allele naming scheme and genotype inference method for adaptive immune receptor sequencing, validated with genomic long read data and implemented in an R package.

bioRxiv · Dec 26, 2022 · PreprintImmunology

Characterization of Extensive Diversity In Immunoglobulin Light Chain Variable Germline Genes Across Biomedically Important Mouse Strains

J. T. Kos, Y. Safonova, K. M. Shields, C. A. Silver, W. D. Lees, A. M. Collins, C. T. Watson

The paper catalogs germline immunoglobulin light chain variable genes in 18 mouse strains, finding extensive undocumented diversity not present in IMGT.

bioRxiv · May 1, 2022Immunology