Author

J. T. Kos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 3 Organism:mouse· 3 Assay:scRNA-seq· 3 Approach:deep learning· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. T. Watson· 5 shared M. L. Smith· 3 shared W. S. Gibson· 3 shared A. M. Collins· 2 shared A. Peres· 2 shared C. A. Silver· 2 shared C. E. Busse· 2 shared G. Deikus· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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5 shared papersImmunology

C. T. Watson

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Author profile →

5 papers

Recent·Most cited

FLAIRR-seq: A novel method for single molecule resolution of near full-length immunoglobulin heavy chain repertoires

E. E. Ford, D. Tieri, O. L. Rodriguez, N. J. Francoeur, J. Soto, J. T. Kos, A. Peres, W. S. Gibson, C. A. Silver, G. Deikus, E. Hudson, C. R. Woolley, N. Beckmann, A. Charney, T. C. Mitchell, , M. L. Smith

FLAIRR-seq provides high-resolution, single-molecule characterization of immunoglobulin heavy chain repertoires, including constant region features, and identifies novel alleles.

bioRxiv · Sep 24, 2022 · PreprintImmunology

Characterization of Extensive Diversity In Immunoglobulin Light Chain Variable Germline Genes Across Biomedically Important Mouse Strains

J. T. Kos, Y. Safonova, K. M. Shields, C. A. Silver, W. D. Lees, A. M. Collins, C. T. Watson

The paper catalogs germline immunoglobulin light chain variable genes in 18 mouse strains, finding extensive undocumented diversity not present in IMGT.

bioRxiv · May 1, 2022Immunology

A BALB/c IGHV Reference Set, defined by haplotype analysis of long-read VDJ-C sequences from F1 (BALB/c / C57BL/6) mice

K. J. Jackson, J. T. Kos, W. Lees, W. S. Gibson, M. L. Smith, A. Peres, G. Yaari, M. Corcoran, C. E. Busse, M. Ohlin, C. T. Watson, A. M. Collins

The paper defines a BALB/c IGHV reference set by analyzing long-read VDJ-C sequences from F1 mice, identifying strain-specific variations and germline alleles not present in existing genome references.

bioRxiv · Feb 28, 2022Immunology

Vaccine genetics of IGHV1-2 VRC01-class broadly neutralizing antibody precursor naive human B cells

J. H. Lee, L. Toy, J. T. Kos, Y. Safonova, W. R. Schief, C. T. Watson, C. Havenar-Daughton, S. Crotty

The paper screens naive B cells for VRC01-class broadly neutralizing antibody precursors using a germline-targeting immunogen and single-cell BCR sequencing, finding common germline variation affecting gene usage.

bioRxiv · Mar 1, 2021Immunology

A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild-derived and classical inbred mouse strains

C. T. Watson, J. T. Kos, W. S. Gibson, C. E. Busse, L. Newman, G. Deikus, M. L. Smith, K. J. Jackson, A. M. Colins

The paper compares immunoglobulin gene diversity in wild-derived and classical inbred mouse strains, finding novel alleles and highlighting genetic complexity in IGH loci.

bioRxiv · Aug 7, 2019Immunology