Author

W. H. J. Beck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Y. Mao· 2 shared A. Akturk· 1 shared A. Sulpizio· 1 shared J. P. Vogel· 1 shared L. K. Nicholson· 1 shared M. B. Smolka· 1 shared M. Lanz· 1 shared M. Wan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Y. Mao

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintFeb 13, 2022

Solution structure of the phosphatidylinositol 3-phosphate binding domain from the Legionella effector SetA

W. H. J. Beck, T. A. Enoki, X. Wu…·Y. Mao

The paper reports the NMR solution structure of the SetA-CTD domain from Legionella pneumophila, revealing its PI(3)P binding mechanism and structural features important for membrane association.

DOI 10.1101/2022.02.13.480292

protein structureexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivAug 23, 2019

Deubiquitination of phosphoribosyl-ubiquitin conjugates by PDE domain-containing Legionella effectors

M. Wan, A. Sulpizio, A. Akturk…·Y. Mao

This paper identifies DupA and DupB as deubiquitinases that reverse PR-ubiquitination, a novel modification mediated by Legionella effectors, and shows their role in modulating host-pathogen interactions.

DOI 10.1073/pnas.1916287116

humanproteomics

𝕏 PostBluesky