Author

W. M. Yeshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

C. Y. Chiang· 2 shared H. S. Dhekne· 2 shared S. R. Pfeffer· 2 shared A. Adhikari· 1 shared C. Limouse· 1 shared D. R. Alessi· 1 shared E. Jaimon· 1 shared E. Purlyte· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

C. Y. Chiang

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Author profile →

2 papers

Recent·Most cited

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 27, 2023

Localization of PPM1H phosphatase tunes Parkinsons disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis

W. M. Yeshaw, A. Adhikari, C. Y. Chiang…·S. R. Pfeffer

This paper shows that PPM1H phosphatase localization affects its ability to dephosphorylate Rab GTPases, influencing ciliogenesis and membrane trafficking.

DOI 10.1073/pnas.2315171120

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivFeb 17, 2023

Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase

H. S. Dhekne, F. Tonelli, W. M. Yeshaw…·S. R. Pfeffer

The paper identifies Rab12 as a critical activator of pathogenic LRRK2 kinase through a CRISPR-based screen and structural analysis.

DOI 10.7554/elife.87098

mouseproteomics

𝕏 PostBluesky