Author

W. Pearce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

B. Mahler-Araujo· 1 shared B. Vanhaesebroeck· 1 shared N. McGranahan· 1 shared R. Knox· 1 shared R. Madsen· 1 shared R. Semple· 1 shared S. Lopez· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

B. Mahler-Araujo

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1 paper

Recent·Most cited

Oncogenic PIK3CA promotes cellular stemness in an allele dose-dependent manner

R. Madsen, R. Knox, W. Pearce, S. Lopez, B. Mahler-Araujo, N. McGranahan, B. Vanhaesebroeck, R. Semple

This study shows that homozygous PIK3CAH1047R mutations in iPSCs lead to cancer-like changes, while heterozygous mutations do not, highlighting allele dose-dependent effects.

bioRxiv · Dec 13, 2018Cancer Biology