Author

W. Richard McCombie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:genome assembly· 2 Assay:long-read sequencing· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:multiple species· 1

Frequent Co-Authors

Hayan Lee· 2 shared James Gurtowski· 2 shared Sara Goodwin· 2 shared Shoshana Marcus· 2 shared Christopher M. Hammell· 1 shared Cristina Aguirre-Chen· 1 shared Ethan Alexander García BakeriD· 1 shared Maria Nattestad· 1 shared

Activity by Year

2014-2016 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBioinformatics

Hayan Lee

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SiLiCO: A Simulator of Long Read Sequencing in PacBio and Oxford Nanopore

Ethan Alexander García Baker, Sara Goodwin, W. Richard McCombie, Olivia Mendivil Ramos

SiLiCO simulates long read sequencing data from PacBio and Oxford Nanopore to assess sequencing failure mechanics and provide standardized reference datasets.

bioRxiv · Sep 22, 2016 · PreprintGenomics

C. elegans PVD Neurons: A Platform for Functionally Validating and Characterizing Neuropsychiatric Risk Genes

Cristina Aguirre-Chen, Nuri Kim, Olivia Mendivil Ramos, Melissa Kramer, W. Richard McCombie, Christopher M. Hammell

The paper uses C. elegans PVD neurons to functionally validate neuropsychiatric risk genes, identifying 7 genes critical for neuronal development.

bioRxiv · May 17, 2016 · PreprintNeuroscience

Third-generation sequencing and the future of genomics

Hayan Lee, James Gurtowski, Shinjae Yoo, Maria Nattestad, Shoshana Marcus, Sara Goodwin, W. Richard McCombie, Michael C. Schatz

This paper discusses third-generation sequencing technologies and their potential to improve genome assembly, structural variation analysis, and haplotype phasing.

bioRxiv · Apr 13, 2016 · PreprintBioinformatics

Error correction and assembly complexity of single molecule sequencing reads.

Hayan Lee, James Gurtowski, Shinjae Yoo, Shoshana Marcus, W. Richard McCombie, Michael Schatz

This paper evaluates the impact of long-read sequencing on genome assembly across multiple species and introduces a new error correction algorithm and predictive model.

bioRxiv · Jun 18, 2014 · PreprintBioinformatics