Author

W. Winkler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Akalin· 2 shared A. Rosenwald· 2 shared I. Anagnostopoulos· 2 shared K. Rajewsky· 2 shared M. Janz· 2 shared A. Heuser· 1 shared A. Pfaus· 1 shared A. Rahjouei· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. Akalin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A new type of transcriptional reprogramming by an IRF4 mutation in lymphoma

N. Schleussner, P. Cauchy, V. Franke, M. Giefing, O. Fornes, N. Vankadari, S. Assi, M. Costanza, M. A. Weniger, A. Akalin, I. Anagnostopoulos, T. Bukur, M. G. Casarotto, F. Damm, O. Daumke, , R. Grosschedl

This study identifies a mutation in IRF4 that alters DNA-binding specificity and gene regulation in lymphoma, leading to disease-specific gene up-regulation.

bioRxiv · Dec 29, 2022 · PreprintCancer Biology

Preclinical models of human multiple myeloma subgroups

W. Winkler, C. Farre Diaz, E. Blanc, H. Napieczynska, P. Langner, M. Werner, B. Walter, B. Wollert-Wulf, T. Yasuda, A. Heuser, D. Beule, S. Mathas, I. Anagnostopoulos, A. Rosenwald, K. Rajewsky, M. Janz

This study generates preclinical models of human multiple myeloma subgroups by inducing specific genetic alterations in mice, showing their resemblance to human disease.

bioRxiv · Aug 28, 2021 · PreprintCancer Biology

Pdap1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

V. Delgado-Benito, M. Berruezo-Llacuna, R. Altwasser, W. Winkler, S. Balasubramanian, D. Sundaravinayagam, R. Graf, A. Rahjouei, M. Driesner, L. Keller, M. Janz, A. Akalin, M. Di Virgilio

This study identifies Pdap1 as a regulator of mature B cell survival and antibody gene diversification by modulating the integrated stress response and AID expression.

bioRxiv · Jan 30, 2020Immunology