Cryo-EM complex structure of active GPR75 with a nanobody
Z. Lv, Y. He, Y. Xiang, J. Li, F. Meng, H. Zhao, H. Guo, D. He, Y. Wang, W. Zhuo, Y. Liu, X. Ni, J. Heng
The paper reports the Cryo-EM structure of active GPR75 with a nanobody, revealing its activation mechanism and providing a structural basis for anti-obesity drug discovery.
bioRxiv · Aug 18, 2022 · PreprintBiophysics