Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapy
D. E. Anderson, J. Cui, Q. Ye, B. Huang, W. Zu, J. Gong, W. Liu, S. Y. Kim, B. G. Yan, K. Sigmundsson, X. F. Lim, F. Ye, P. Niu, X. Zhou, W. Tan, , X. Tan
The paper identifies MTHFD1 as a target for broad antiviral therapy by screening bat cells with RNAi and CRISPR libraries against mumps and influenza viruses.
bioRxiv · Mar 29, 2020Microbiology