Behavioral effect of chemogenetic inhibition is directly related to receptor transduction levels in rhesus monkeys
Nicholas A. Upright, Stephen W. Brookshire, Wendy Schnebelen, Christienne G. Damatac, Patrick R. Hof, Philip G. F. Browning, Paula L. Croxson, Peter H. Rudebeck, Mark G. Baxter
This study shows that chemogenetic inhibition in rhesus monkeys affects behavior based on the level of receptor transduction, with higher transduction linked to greater behavioral impairment.
Journal of Neuroscience · Aug 6, 2018Peer-reviewedNeuroscience