The paper examines longitudinal ADHD symptom changes linked to white matter microstructure using fixel-based analysis, finding associations between symptom improvement and specific tract metrics.

NeuroImage Clinical · Jan 1, 2022Peer-reviewedNeuroscience

Associations between ADHD symptom remission and white matter microstructure: a longitudinal analysis

Anne E. M. Leenders, Christienne G. Damatac, Sourena Soheili‐Nezhad, Roselyne J. Chauvin, Maarten Mennes, Marcel P. Zwiers, D. vanRooij, Sophie E.A. Akkermans, Jilly Naaijen, Barbara Franke, Jan K. Buitelaar, Christian F. Beckmann, Emma Sprooten

This study examines how white matter microstructure changes longitudinally in relation to ADHD symptom remission in adolescents and young adults.

bioRxiv · Sep 24, 2020 · PreprintNeuroscience

White matter microstructure in attention-deficit/hyperactivity disorder: a systematic tractography study in 654 individuals

Christienne G. Damatac, Roselyne J. Chauvin, Marcel P. Zwiers, Daan van Rooij, Sophie E.A. Akkermans, Jilly Naaijen, Pieter J. Hoekstra, Catharina Annette Hartman, Jaap Oosterlaan, Barbara Franke, Jan K. Buitelaar, Christian F. Beckmann, Emma Sprooten

The paper investigates white matter microstructure in ADHD using tractography, finding no significant FA associations with diagnosis but links lower FA in the right cingulum angular bundle to hyperactivity/impulsivity symptoms.

Biological Psychiatry Cognitive Neuroscience and Neuroimaging · Aug 1, 2020Peer-reviewedNeuroscience

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

Rachel M. Brouwer, Marieke Klein, Katrina L. Grasby, Hugo Gerard Schnack, Neda Jahanshad, Jalmar Teeuw, Sophia I. Thomopoulos, Emma Sprooten, Carol E. Franz, Nitin Gogtay, William S. Kremen, Matthew S. Panizzon, Loes M. Olde Loohuis, Christopher D. Whelan, Moji Aghajani, , Andreas J. Forstner

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.

bioRxiv · Apr 24, 2020 · PreprintGenetics

Behavioral effect of chemogenetic inhibition is directly related to receptor transduction levels in rhesus monkeys

Nicholas A. Upright, Stephen W. Brookshire, Wendy Schnebelen, Christienne G. Damatac, Patrick R. Hof, Philip G. F. Browning, Paula L. Croxson, Peter H. Rudebeck, Mark G. Baxter

This study shows that chemogenetic inhibition in rhesus monkeys affects behavior based on the level of receptor transduction, with higher transduction linked to greater behavioral impairment.

Journal of Neuroscience · Aug 6, 2018Peer-reviewedNeuroscience

An open resource for nonhuman primate imaging

Michael Peter Milham, Lei Ai, Bonhwang Koo, Ting Xu, Fabien Balezeau, Mark G. Baxter, Paula L. Croxson, Christienne G. Damatac, Noam Harel, Winrich A. Freiwald, Timothy David Griffiths, Stefan Everling, Benjamin Jung, Sabine Kästner, David A. Leopold, , Charles E. Schroeder

The paper introduces PRIME-DE, an open resource for non-human primate MRI data, aggregating 13 datasets from 11 sites across 98 macaques.

bioRxiv · Nov 30, 2017 · PreprintNeuroscience

Lack of evidence for sex differences in higher cognitive function in macaques

Jamie Nagy, Christienne G. Damatac, Mark G. Baxter, Peter H. Rudebeck, Paula L. Croxson

This study finds no sex differences in higher cognitive function between male and female rhesus monkeys in episodic memory and strategy implementation tests.

bioRxiv · Jun 21, 2017 · PreprintNeuroscience