Peter H. Rudebeck

The paper introduces Seq-o-Matic, an open-source automated in situ sequencer that reduces hands-on time and improves sequencing consistency across tissue sections.

This paper introduces CURBD, a method using data-constrained recurrent neural networks to infer brain-wide interactions from neural recordings across species.

The paper shows that during decision-making, neural activity in frontal and subcortical areas dynamically changes, with geometry shifts reflecting decision difficulty and option evaluation.

This study shows that deep brain stimulation remodels white matter and alters brain-wide functional connectivity in macaques, contributing to its therapeutic effects.

The paper compares limbic-frontal connectivity across seven primate species, finding conserved connection patterns and differences in subgenual cingulum bundle connectivity.

This study investigates the role of amygdala to ventrolateral prefrontal cortex (vlPFC) projections in contingent learning by inhibiting these connections in macaques and observing effects on reward signaling and choice memory.

The paper identifies consistent hierarchical timescales of single neurons across mice, macaques, and humans, with species-specific variations in certain brain regions.

This study examines the effects of D1 and D2 receptor antagonists on probabilistic learning and brain connectivity in macaques, revealing distinct neural networks associated with learning and motivation.

This study investigates how vlPFC activity and connectivity guide decision-making in different learning contexts using rhesus macaques.

The paper investigates dynamic inter-areal communication in macaque ventral frontal cortex during decision-making, finding temporally specific and task-dependent patterns of connectivity.

The paper records neural activity in eight subdivisions of macaque ventral frontal cortex during a decision-making task and finds dissociable representations of decision variables across these regions.

The paper compares single-neuron projection patterns from the basolateral amygdala to the frontal cortex in mice and macaques, finding differences in connectivity organization.

This study uses chemogenetic manipulation in macaques to show that activating inhibitory DREADDs in the amygdala increases resting-state fMRI functional connectivity between the amygdala and ventrolateral prefrontal cortex.

The paper identifies two separable valuation systems in prefrontal-limbic circuits of macaque monkeys, with one in OFC representing outcome flavor and another in vlPFC representing outcome probability.

The paper uses MAPseq to analyze BLA neuron projections in macaques, finding that many neurons project to multiple brain regions and form structured networks.

The paper identifies temporally specific neural activity patterns in subcallosal ACC, striatum, and amygdala during reward anticipation in non-human primates.

This study uses resting-state fMRI to screen deschloroclozapine in rhesus macaques, showing dosage-dependent changes in brain connectivity and behavioral effects.

The paper investigates how bodily arousal affects decision-making in macaques by analyzing neural activity in the orbitofrontal cortex and dorsal anterior cingulate cortex, showing changes in HR encoding after amygdala lesions.

The paper identifies a theta band network in the prefrontal and temporal lobes that is uniquely activated during episodic memory tasks in humans.

This study shows that chemogenetic inhibition in rhesus monkeys affects behavior based on the level of receptor transduction, with higher transduction linked to greater behavioral impairment.

This study investigates the effects of Aβ oligomers on synaptic pathology and neuroinflammation in a female rhesus monkey model of Alzheimer’s disease, finding significant synaptic loss and inflammatory responses.

This study finds no sex differences in higher cognitive function between male and female rhesus monkeys in episodic memory and strategy implementation tests.

The paper investigates how amygdala input differentially affects prefrontal cortex encoding of reward-based decisions through local field potentials and single neuron activity in monkeys.