Author

Nicholas A. Upright

Icahn School of Medicine at Mount SinaiORCID 0000-0001-5479-609XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2

Frequent Co-Authors

Mark G. BaxteriD· 2 shared Christienne G. DamataciD· 1 shared Patrick R. HofiD· 1 shared Paula L. CroxsoniD· 1 shared Peter H. RudebeckiD· 1 shared Philip G. F. BrowningiD· 1 shared Stephen W. BrookshireiD· 1 shared Wendy Schnebelen· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersNeuroscience

Mark G. BaxterORCID

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2 papers

Recent·Most cited

NeuroscienceNeuropsychopharmacologyPeer-reviewedMar 19, 2020

Chemogenetic actuator drugs impair prefrontal cortex-dependent working memory in rhesus monkeys

Nicholas A. Upright, Mark G. Baxter

This study tests the effects of three DREADD actuator drugs on working memory in rhesus monkeys, finding dose-dependent impairments in some monkeys.

47 citations

ratexperimental assay

𝕏 PostBluesky

NeuroscienceJournal of NeurosciencePeer-reviewedAug 6, 2018

Behavioral effect of chemogenetic inhibition is directly related to receptor transduction levels in rhesus monkeys

Nicholas A. Upright, Stephen W. Brookshire, Wendy Schnebelen…·Mark G. Baxter

This study shows that chemogenetic inhibition in rhesus monkeys affects behavior based on the level of receptor transduction, with higher transduction linked to greater behavioral impairment.

69 citationstop 4%

ratexperimental assay

𝕏 PostBluesky