Author

Werner Koopman

Radboud University Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:graph neural network· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Adelaide Maria Fernandes Borralho· 1 shared Alain Geille· 1 shared Albert Carbonell· 1 shared Alessandro PrigioneiD· 1 shared Alex Garanto· 1 shared Alex Mackenzie· 1 shared Anastasia KritharaiD· 1 shared Anastasios NentidisiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Adelaide Maria Fernandes Borralho

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2 papers

Recent·Most cited

Resting state fMRI detects pathological functional brain connectivity in the Ndufs4 knockout mouse model of Leigh syndrome during the pre-symptomatic stage of the disease

Chao Ciu-Gwok Guo, Melissa van de Wal, Samir el Bouazzati, Noortje M. P. Overwater, Lianne Remie, Werner Koopman, Joanes Grandjean, Judith Regina Homberg

The paper uses rs-fMRI to detect altered functional connectivity in Ndufs4 knockout mice during the pre-symptomatic stage of Leigh syndrome, finding increased connectivity in multiple brain regions and no effect of KH176 treatment.

bioRxiv · Oct 24, 2026 · PreprintNeuroscience

KG-Bench: Benchmarking Graph Neural Network Algorithms for Drug Repurposing

Siqi Wei, Christo Sasi, Jelle Piepenbrock, Martijn A. Huynen, Peter A.C. ’t Hoen, Tessa Braam, Esther Bührman, Juliette Chevalier, Martina Cornelia Cornel, Lotte Haverman, Vivi Majella Heine, Annelieke R. Müller, Tessel Rigter, Tom Steenbergen, Clara van Karnebeek, , Sara Pintado

KG-Bench benchmarks graph neural networks for drug repurposing using the Open Targets dataset, finding TransformerConv achieves the highest performance.

Bioinformatics · May 7, 2026Peer-reviewedBioinformatics