Author

William C. Joesten

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:trajectory inference· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

BumJin KoiD· 2 shared Changyang LinghuiD· 2 shared Denise J. CaiiD· 2 shared Donglai WeiiD· 2 shared Dongqing ShiiD· 2 shared Jormay LimiD· 2 shared Lirong ZhengiD· 2 shared Mehul GautamiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

BumJin KoORCID

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2 papers

Recent·Most cited

Simultaneous brain-wide single-cell recording resolves spatiotemporal memory architecture

Dongqing Shi, Yongjie Hou, Yixiao Yan, Tian-hao Zhang, William C. Joesten, Peng Liu, Yixuan Wang, Mehul Gautam, Jormay Lim, Lirong Zheng, Jonathan Gould, BumJin Ko, Xiaoman Niu, Mou-Chi Cheng, Jung‐Chien Hsieh, , Changyang Linghu

The paper introduces GLOBE, a brain-wide single-cell recording technology, and demonstrates its use in capturing Fos transcriptional activity across a mouse brain over time.

bioRxiv · May 22, 2026 · PreprintNeuroscience

Multiplexed, scalable analog recording of gene regulation dynamics over weeks using intracellular protein tapes

Lirong Zheng, Dongqing Shi, Yixiao Yan, Bingxin Zhou, Jormay Lim, Yongjie Hou, Bobae An, Jason Ken Adhinarta, Michael Lin, BumJin Ko, William C. Joesten, Mehul Gautam, Elie D.M. Huez, Eung Chang Kim, Emily Klyder, , Changyang Linghu

This paper introduces CytoTape, a tool for continuous, multiplexed recording of gene regulation dynamics over weeks at single-cell resolution, and demonstrates its use in measuring transcription factor activities.

Nature · Jan 26, 2026Peer-reviewedSynthetic Biology