Author

William G Dowell

University of Vermont

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Devdoot S. MajumdariD· 1 shared Hana PaculováiD· 1 shared Jacob S. DearborniD· 1 shared Jade H Cleary· 1 shared Kalev FreemaniD· 1 shared Seth E. FrietzeiD· 1 shared Sylvester LanguoniD· 1 shared Tylar Kirch· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Devdoot S. MajumdarORCID

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1 paper

Recent·Most cited

Genome-Wide CRISPRi Screening Identifies XPO5 as a Regulator of B Cell Mutation and Fitness

Tylar Kirch, Zachary D. Miller, Jacob S. Dearborn, William G Dowell, Sylvester Languon, Hana Paculová, Jade H Cleary, Seth E. Frietze, Kalev Freeman, Devdoot S. Majumdar

This study identifies XPO5 as a regulator of B cell receptor surface expression through a genome-wide CRISPRi screen, showing its role in balancing mutagenesis and DNA repair during somatic hypermutation.

bioRxiv · Apr 24, 2026 · PreprintCell Biology