A Trans-Omic Mendelian Randomization Study of Parental Lifespan Uncovers Novel Aging Biology and Drug Candidates for Human Healthspan Extension
Nicolas Perrot, William Pelletier, Jérôme Bourgault, Christian Couture, Zhonglin Li, Patricia L. Mitchell, Nooshin Ghodsian, Yohan Bossé, Sébastien Thériault, Patrick Mathieu, Benoît J. Arsenault
This study uses trans-omic Mendelian randomization to identify genes, proteins, and metabolites associated with parental lifespan and potential drug targets for healthspan extension.
Aging Cell · Oct 27, 2021Peer-reviewedGenetic & Genomic Medicine