Author

Philippe Pîbarot

Institut universitaire de cardiologie et de pneumologie de QuébecORCID 0000-0002-3607-279XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 2 Assay:bulk RNA-seq· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Patrick MathieuiD· 4 shared Sébastien ThériaultiD· 4 shared Yohan BosséiD· 4 shared Benoît J. ArsenaultiD· 3 shared Marie-Annick A ClaveliD· 3 shared Romain CapouladeiD· 3 shared Christian Dina CiD· 2 shared David Messika–ZeitouniD· 2 shared

Activity by Year

2018-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Patrick MathieuORCID

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Author profile →

4 papers

Recent·Most cited

Genetic association analyses highlight IL6, ALPL, and NAV1 as three new susceptibility genes underlying calcific aortic valve stenosis

Sébastien Thériault, Christian Dina C, David Messika–Zeitoun, Solena Le Scouarnec, Romain Capoulade, Nathalie Gaudreault, Sidwell Rigade, Zhonglin Li, Floriane Simonet, Maxime Lamontagne, Marie-Annick A Clavel, Benoît J. Arsenault, Anne‐Sophie Boureau, Simon Lecointe, Estelle Baron, , Sylviane Vol

This study identifies three new susceptibility genes for calcific aortic valve stenosis through GWAS and TWAS, highlighting roles in inflammation, mineralization, and blood vessel integrity.

Circulation Genomic and Precision Medicine · Oct 1, 2019Peer-reviewedGenomics

Long-Term Exposure to Elevated Lipoprotein(a) Levels, Parental Lifespan and Risk of Mortality

Benoît J. Arsenault, William Pelletier, Yannick Kaiser, Nicolas Perrot, Christian Couture, Kay‐Tee Khaw, Nicholas J. Wareham, Yohan Bossé, Philippe Pîbarot, Erik S.G. Stroes, Patrick Mathieu, Sébastien Thériault, S. Matthijs Boekholdt

This study investigates the association between elevated Lp(a) levels, parental lifespan, and long-term mortality risk using genetic and observational data.

bioRxiv · Apr 29, 2019 · PreprintGenetics

Genetic inhibition of PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis

Nicolas Perrot, Donato Moschetta, S. Matthijs Boekholdt, Vincenza Valerio, Andreas Martinsson, Romain Capoulade, Elvira Mass, Marie-Annick A Clavel, Nicholas J. Wareham, Christian Dina C, Hao Yu Chen, James C. Engert, George Thanassoulis, Patrick Mathieu, Yohan Bossé, , Benoît J. Arsenault

This study shows genetic inhibition of PCSK9 lowers lipoprotein levels and reduces risk of CAD and CAVS, with PCSK9 present in calcified aortic valves and induced by oxidative stress.

bioRxiv · Mar 1, 2019 · PreprintGenetics

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

Sébastien Thériault, Nathalie Gaudreault, Maxime Lamontagne, Mickaël Rosa, Marie‐Chloé Boulanger, David Messika–Zeitoun, Marie-Annick A Clavel, Romain Capoulade, François Dagenais, Philippe Pîbarot, Patrick Mathieu, Yohan Bossé

Nature Communications · Mar 1, 2018Peer-reviewedGenomics