Transcriptional Elongation-Associated RNA Processing Errors in Induced Cellular Growth Arrest
Saeid Mohammad Parast, Simai Wang, Marta Iwanaszko, Yue He, Deniz G. Olgun, Sarah R. Gold, Yuki Aoi, Jacob M. Zeidner, Benjamin C. Howard, William R. Thakur, Vijay Ramani, Ali Shilatifard
The paper identifies ELOA-dependent mechanisms regulating transcription maturation and links them to cellular senescence and aging through RNA processing defects and growth arrest.
bioRxiv · Jun 23, 2025 · PreprintMolecular Biology