Marta Iwanaszko

The paper identifies and characterizes FCD-11, a first-in-class COMPASS inhibitor that reduces tumor size and extends survival in breast cancer models.

This study identifies MeCP2's interaction with the super elongation complex and shows it regulates transcription by modulating RNA polymerase II binding and gene expression.

This study shows BRD2 promotes transcriptional initiation via bromodomain-dependent binding to acetylated histones and recruits TFIID, while BRD4 mediates elongation through CDK9 recruitment.

The paper identifies ELOA-dependent mechanisms regulating transcription maturation and links them to cellular senescence and aging through RNA processing defects and growth arrest.

This study shows that dietary restriction in Drosophila affects diurnal rhythms and longevity through clock-controlled proteasome subunits.

TimeTrial evaluates cycle detection algorithms in circadian transcriptomics by analyzing real and synthetic data to optimize experimental design and analysis choices.

This paper develops a Drosophila model for TBI and identifies glial immune pathways as mediators of TBI effects on behavior.